Title :
A digital microfluidic processor for biomedical applications
Author :
Lai, Kelvin Yi-Tse ; Yu-Tao Yang ; Wang, Guibin ; Yi-Wen Lu ; Chen-Yi Lee
Author_Institution :
Dept. of Electron. Eng. & Inst. of Electron., Nat. Chiao-Tung Univ., Hsinchu, Taiwan
Abstract :
A digital microfluidic processor for biomedical detection is presented. This processor integrates the functions of droplet actuation, droplet position/shape/volume detection and capacitive measurement window to demonstrate a novel prototype for personalize medicine. In this proposed system, the location map of micro droplets and reaction behaviors are visible on 2-dimensional (2D) graphical user-interface due to capacitive sensing technology and hence automatic signal processing is achievable. Fabricated in standard 0.35um 2P4M CMOS process, this test chip integrates 900 microelectrodes with measurement window in 3.2mm2. Measurement results show that operation of microdroplets moving is under 1 KHz and digital signal extractions of position detection and statistical analysis are under 1 MHz respectively.
Keywords :
CMOS integrated circuits; biomedical electrodes; capacitance measurement; graphical user interfaces; medical signal processing; microfluidics; microprocessor chips; statistical analysis; 2-dimensional graphical user-interface; 2P4M CMOS process; automatic signal processing; biomedical detection; capacitive measurement window; capacitive sensing technology; digital microfluidic processor; digital signal extractions; droplet actuation; droplet position-shape-volume detection; microdroplets; microelectrodes; position detection; size 0.35 mum; statistical analysis; Bioassays; Biochip; Biomedical Processor; Capacitive Sensing; EWOD; Microfluidics;
Conference_Titel :
Signal Processing Systems (SiPS), 2013 IEEE Workshop on
Conference_Location :
Taipei City
DOI :
10.1109/SiPS.2013.6674480
