DocumentCode
651450
Title
Output stage of a current-steering multipolar and multisite deep brain stimulator
Author
Valente, Virgilio ; Demosthenous, Andreas ; Bayford, Richard
Author_Institution
Dept. of Electr. & Electron. Eng., Univ. Coll. London, London, UK
fYear
2013
fDate
Oct. 31 2013-Nov. 2 2013
Firstpage
85
Lastpage
88
Abstract
Clinical deep brain stimulation (DBS) is based on the use of cylindrical electrodes driven in monopolar or bipolar configurations. The simulation field spreads symmetrically around the electrode modulating both targeted and non-targeted neural structures. Recent advances have focused on novel stimulation techniques based on the use of high-density segmented electrodes, which allow current-steering and field-shaping capability. This paper presents the architecture of a multi-channel current-steering stimulator output stage that allows for monopolar, bipolar, tripolar and quadripolar multi-site stimulation. The core of the output stage comprises N independent high-compliance current drivers (HCCDs), capable of delivering up to 1.5 mA complementary currents in 10 different current ranges. Each of the N HCCDs can drive up to 8 adjacent electrode contacts thanks to a 2-32 multiplexer controlled by a 5-32 decoder. The HCCD was designed in a HV 0.18μm CMOS process. The circuits were simulated in Cadence Spectre and simulated results are presented in the paper.
Keywords
CMOS integrated circuits; biomedical electrodes; brain; multiplexing equipment; neurophysiology; CMOS; HCCD; N independent high-compliance current drivers; bipolar configurations; clinical deep brain stimulation; current-steering capability; current-steering multipolar; cylindrical electrodes; field-shaping capability; high-density segmented electrodes; monopolar configurations; multichannel current-steering stimulator; multiplexer; multisite deep brain stimulator; nontargeted neural structures; quadripolar multisite stimulation; tripolar multisite stimulation; Brain stimulation; Decoding; Electrodes; MOSFET; Radio frequency; Resistors; Satellite broadcasting;
fLanguage
English
Publisher
ieee
Conference_Titel
Biomedical Circuits and Systems Conference (BioCAS), 2013 IEEE
Conference_Location
Rotterdam
Type
conf
DOI
10.1109/BioCAS.2013.6679645
Filename
6679645
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