• DocumentCode
    652413
  • Title

    Utilization of Default Logic for Analyzing a Metabolic System in Discrete Time

  • Author

    Tan Le ; Doncescu, Andrei ; Siegel, P.

  • Author_Institution
    Lab. for Anal. & Archit. of Syst., Univ. of Toulouse, Toulouse, France
  • fYear
    2013
  • fDate
    24-27 June 2013
  • Firstpage
    130
  • Lastpage
    136
  • Abstract
    Metabolic pathways are seen as high criticalities in our understanding of mechanisms of biological functions. This article focuses on automatic synthesis of the metabolic pathways from factors in the domain of discrete time. An essential component of this approach is using default logic to acquire facts about biological knowledge of intracellular communication. By choosing an adequate representation of biological knowledge, the "reasoning" is able to assign in acquisition of the facts and extract interactions necessary for the synthesis of the metabolic pathways or signaling.
  • Keywords
    biology computing; formal logic; inference mechanisms; knowledge representation; automatic metabolic pathways synthesis; biological functions; biological knowledge; biological knowledge representation; default logic utilization; discrete time; intracellular communication; metabolic pathways; metabolic system; reasoning; Biological system modeling; Equations; Mathematical model; Production; Proteins;
  • fLanguage
    English
  • Publisher
    ieee
  • Conference_Titel
    Computational Science and Its Applications (ICCSA), 2013 13th International Conference on
  • Conference_Location
    Ho Chi Minh City
  • Type

    conf

  • DOI
    10.1109/ICCSA.2013.27
  • Filename
    6681110