Detection of benzene series by two-dimensional FAIMS technique

Benzene, toluene, p-xylene, m-xylene and o-xylene are harmful to human body seriously, moreover, p-xylene, m-xylene and o-xylene are isomers, which are difficult to distinguish by commonly used spectrum analysis techniques, such as mass spectrometry. In this article, they were detected by using high field asymmetric waveform ion mobility spectrometry (FAIMS). The resolution of detecting samples was optimized by two dimensional scanning concerning the compensation voltage in combination with high dispersion voltage. FAIMS has good solution to identify them. According to the experimental results, we obtained two-dimensional spectra. By fitting of equations about electric field intensity, we worked out second-order and fourth-order coefficient of ion mobility nonlinear function, which is useful to establish characteristic FAIMS spectra of the benzene series compounds.