Title :
Embedded device for simultaneous recording and stimulation for retina implant research
Author :
Schloesser, M. ; Cota, O. ; Heil, R. ; Brusius, J. ; Offenhausser, A. ; Waasen, S.V. ; Schiek, M.
Author_Institution :
Central Inst. for Eng., Electron. & Analytics (ZEA-2), Forschungszentrum Juelich GmbH, Julich, Germany
Abstract :
Simultaneous stimulation and recording of retinal nerve cells with penetrating three dimensional multi-electrode arrays (MEA) on a localized area is a demanding challenge in next generation retina implant research. Within the scope of this research we developed a device to stimulate a network of bi-polar cells and record retinal ganglion cells with a slight time gap to overcome long recording dead times and switching artifacts in common stimulation- and recording systems. The device contains a four channel stimulator capable of pushing arbitrary bi-polar charges into the tissue and a 16 channel commercial electrophysiology interface chip. The device is a miniaturized front-end for our former developed embedded wireless communicating sensor node. First tests in in-vitro retina slices on adult rat with our device show reliable recordings of ganglia cell activity below 1ms after the bi-polar cell stimulation.
Keywords :
bioelectric phenomena; biomedical electrodes; cellular biophysics; embedded systems; eye; neurophysiology; prosthetics; wireless sensor networks; bipolar cell stimulation; electrophysiology interface chip; embedded device; embedded wireless communicating sensor node; retina implant research; retinal ganglion cells; retinal nerve cells; simultaneous recording; simultaneous stimulation; three dimensional multielectrode arrays; Electric potential; Electrodes; Impedance; Implants; Noise; Retina; Wireless communication; embedded system; functional electrical stimulation; neuronal recording; retina implant;
Conference_Titel :
SENSORS, 2013 IEEE
Conference_Location :
Baltimore, MD
DOI :
10.1109/ICSENS.2013.6688173
