Title :
Biopsy analysis using a quadruple infrared sensor
Author :
Fioravanti, Valeria ; Weber, E. ; van den Driesche, S. ; Vellekoop, Michael J. ; Pucciarelli, Daniela ; Breiteneder, Heimo ; Hafner, Christian
Author_Institution :
Inst. for Microsensors, -Actuators & -Syst. (IMSAS/MCB), Univ. of Bremen, Bremen, Germany
Abstract :
In this contribution, infrared absorbance measurements by using a quadruple sensor have been performed for the first time to indicate the presence of cancer cells in melanoma biopsies. To verify the fidelity of the obtained results, they have been compared with results achieved by histopathology analysis and by using Fourier transform infrared (FTIR) spectroscopic imaging of tissue arrays. A significant agreement has been found between the different methods, demonstrating the potential of the quadruple infrared sensor as a label-free and cost-effective instrument to support the experts in their examination and diagnosis of tissue biopsies.
Keywords :
Fourier transform spectroscopy; biological tissues; biomedical measurement; biomedical transducers; cancer; infrared detectors; infrared spectroscopy; FTIR; Fourier transform infrared spectroscopic imaging; cancer cell; histopathology analysis; infrared absorbance measurement; label-free cost-effective instrument; melanoma biopsy analysis; quadruple infrared sensor; tissue biopsy diagnosis; Biopsy; Cancer; Malignant tumors; Microscopy; Sensor systems; Skin;
Conference_Titel :
SENSORS, 2013 IEEE
Conference_Location :
Baltimore, MD
DOI :
10.1109/ICSENS.2013.6688476
