Title :
Intelligent screening for designer drugs: A signal analysis
Author :
Praisler, Mirela ; Ciochina, Silviu
Author_Institution :
“Dunarea de Jos” Univ. of Galati, Galati, Romania
Abstract :
We are presenting an optimized intelligent screening tool built for the automated detection of amphetamines, which represent the main designer drugs found on the black market in Europe. The GC-FTIR spectra of the target compounds were preprocessed with a w2 function that enhances the absorptions identified as having a high modeling and / or discrimination power. The absorptions responsible for the discrimination of amphetamines according to their biological (stimulant and / or hallucinogenic) effect were determined and interpreted. The positive effect of the w2 selective amplifier on the efficiency of the detection system is highlighted by a comparative analysis based on agglomerative clustering.
Keywords :
Fourier transform spectra; chemistry computing; chromatography; drugs; infrared spectra; pattern clustering; signal processing; Europe; Fourier transform infrared spectroscopy; GC-FTIR spectra; absorptions; agglomerative clustering; amphetamines; biological effect; black market; designer drugs; gas chromatography; intelligent screening tool; signal analysis; w2 function; w2 selective amplifier; Absorption; Compounds; Databases; Loading; Principal component analysis; Vectors; Vibrations; Principal Component Analysis; amphetamines; loading plots; selective amplifier;
Conference_Titel :
System Theory, Control and Computing (ICSTCC), 2013 17th International Conference
Conference_Location :
Sinaia
Print_ISBN :
978-1-4799-2227-7
DOI :
10.1109/ICSTCC.2013.6688996
