Title :
Default Logic for Diagnostic of Discrete Time System
Author :
Tan Le ; Doncescu, Andrei ; Siegel, P.
Author_Institution :
Lab. for Anal. & Archit. of Syst., Univ. of Toulouse, Toulouse, France
Abstract :
Signaling pathways are seen as high criticalities in our understanding of mechanisms of biological functions. In this paper, we propose default logic for diagnostic of Discrete Time System (DTS) by focusing on automatic synthesis of the signaling pathways from factors within the cell. An essential component of this approach is using default logic to acquire facts about biological knowledge of intracellular communication. By choosing an adequate representation of biological knowledge, the "reasoning" is able to assign in acquisition of the facts and extract interactions necessary for the synthesis of the signaling pathways.
Keywords :
cellular biophysics; discrete time systems; nonmonotonic reasoning; DTS diagnostic; automatic synthesis; biological functions; biological knowledge; cells; default logic; discrete time system; intracellular communication; reasoning; signaling pathways; Artificial intelligence; Biological system modeling; Cancer; Cognition; Context; Proteins;
Conference_Titel :
Broadband and Wireless Computing, Communication and Applications (BWCCA), 2013 Eighth International Conference on
Conference_Location :
Compiegne
DOI :
10.1109/BWCCA.2013.72