Title :
Prescreening seizure-like events in a rat model of epilepsy A: A 2D video processing method
Author :
Christ, O. ; Somerlik-Fuchs, Karin H. ; Stieglitz, T. ; Schulze-Bonhage, A. ; Hofmann, U.G.
Author_Institution :
Dept. of Neurosurg., Res. Group for Neuroelectron. Syst., Univ. Hosp. Freiburg, Freiburg, Germany
Abstract :
Temporal lobe epilepsy is the most common cause of drug-resistant seizures. Electrical stimulation seems to be a promising alternative to the classical anteromesial temporal resection. Our work aims at improving and validating therapeutic approaches for treating temporal lobe epilepsy using high-frequency stimulation. The relative phase clustering index (rPCI) is used to describe the epileptogenicity of a brain region and seizure prediction. A 2D image processing algorithm is presented for facilitating the tedious and time consuming visual image inspection of long term video footage required to determine optimal electrical stimulation parameters. See our companion paper describing the 3D solution in this journal.
Keywords :
brain; diseases; medical image processing; neuromuscular stimulation; patient rehabilitation; video signal processing; 2D image processing algorithm; 2D video processing; anteromesial temporal resection; brain region; drug-resistant seizure; electrical stimulation; epileptogenicity; high-frequency stimulation; prescreening seizure-like event; rPCI; rat model; relative phase clustering index; seizure prediction; temporal lobe epilepsy; therapeutic approach; visual image inspection; Algorithm design and analysis; Brain modeling; Epilepsy; Histograms; Surgery; Temporal lobe; Time series analysis;
Conference_Titel :
Neural Engineering (NER), 2013 6th International IEEE/EMBS Conference on
Conference_Location :
San Diego, CA
DOI :
10.1109/NER.2013.6695884