Early Detection of risk of autism spectrum disorder based on recurrence quantification analysis of electroencephalographic signals

Early detection of autism spectrum disorder (ASD) in infants is vital in maximizing the impact and potential long-term outcomes of early delivery of rehabilitative therapies. To date no definitive diagnostic test for ASD exists. Electroencephalography is a noninvasive method used to capture underlying electrical changes in brain activity. This proof-of-concept study suggests that recurrence quantification analysis features computed from resting state spontaneous eyes-closed electroencephalographic (EEG) signals may be useful biomarkers for early detection of risk of ASD.