• DocumentCode
    663015
  • Title

    Dynamic finite-element model of axon extracellular stimulation

  • Author

    Henriquez, Fernando ; Jerez-Hanckes, Carlos ; Altermatt, M. D. Fernando R.

  • Author_Institution
    Dept. of Electr. Eng., Pontificia Univ. Catolica de Chile, Santiago, Chile
  • fYear
    2013
  • fDate
    6-8 Nov. 2013
  • Firstpage
    589
  • Lastpage
    592
  • Abstract
    We study the electrical influence of an electrode over an axon of nonzero thickness in time using a two-dimensional finite element formulation. Although our inspiration comes from the practice of peripheral nerve stimulation, other types of neural tissue excitation can benefit from the model. Our formulation combines a Hodgkin-Huxley model to account for nerve dynamics with electrostatic intra- and extracellular potentials. Thus, the influence of external electrode geometry and parameters can be addressed instead of simplifying them to point current sources. We show first numerical results for different extracellular stimuli and explore future enhancement directions.
  • Keywords
    bioelectric potentials; biological tissues; biomedical electrodes; cellular transport; finite element analysis; neurophysiology; physiological models; Hodgkin-Huxley model; axon extracellular stimulation; dynamic finite-element model; electrical influence; electrostatic extracellular potential; electrostatic intracellular potential; external electrode geometry; external electrode parameter; extracellular stimuli; nerve dynamics; neural tissue excitation; nonzero thickness; peripheral nerve stimulation; point current sources; two-dimensional finite element formulation; Electrodes; Equations; Extracellular; Finite element analysis; Mathematical model; Nerve fibers; Voltage measurement;
  • fLanguage
    English
  • Publisher
    ieee
  • Conference_Titel
    Neural Engineering (NER), 2013 6th International IEEE/EMBS Conference on
  • Conference_Location
    San Diego, CA
  • ISSN
    1948-3546
  • Type

    conf

  • DOI
    10.1109/NER.2013.6696003
  • Filename
    6696003