DocumentCode
663015
Title
Dynamic finite-element model of axon extracellular stimulation
Author
Henriquez, Fernando ; Jerez-Hanckes, Carlos ; Altermatt, M. D. Fernando R.
Author_Institution
Dept. of Electr. Eng., Pontificia Univ. Catolica de Chile, Santiago, Chile
fYear
2013
fDate
6-8 Nov. 2013
Firstpage
589
Lastpage
592
Abstract
We study the electrical influence of an electrode over an axon of nonzero thickness in time using a two-dimensional finite element formulation. Although our inspiration comes from the practice of peripheral nerve stimulation, other types of neural tissue excitation can benefit from the model. Our formulation combines a Hodgkin-Huxley model to account for nerve dynamics with electrostatic intra- and extracellular potentials. Thus, the influence of external electrode geometry and parameters can be addressed instead of simplifying them to point current sources. We show first numerical results for different extracellular stimuli and explore future enhancement directions.
Keywords
bioelectric potentials; biological tissues; biomedical electrodes; cellular transport; finite element analysis; neurophysiology; physiological models; Hodgkin-Huxley model; axon extracellular stimulation; dynamic finite-element model; electrical influence; electrostatic extracellular potential; electrostatic intracellular potential; external electrode geometry; external electrode parameter; extracellular stimuli; nerve dynamics; neural tissue excitation; nonzero thickness; peripheral nerve stimulation; point current sources; two-dimensional finite element formulation; Electrodes; Equations; Extracellular; Finite element analysis; Mathematical model; Nerve fibers; Voltage measurement;
fLanguage
English
Publisher
ieee
Conference_Titel
Neural Engineering (NER), 2013 6th International IEEE/EMBS Conference on
Conference_Location
San Diego, CA
ISSN
1948-3546
Type
conf
DOI
10.1109/NER.2013.6696003
Filename
6696003
Link To Document