Organic FET device as a novel sensor for cell bioelectrical and metabolic activity recordings

Organic based transistors for biochemical sensing and cellular applications are becoming an alternative approach to standard technology because of their attractive features (e.g., low-cost, mechanical flexibility, enhanced biocompatibility). A particular configuration of organic FET, namely Organic Charge Modulated FET (OCMFET) is here proposed as a sensor for both electrical and metabolic activity of electroactive cells. Its peculiar structure allows sensing any local charge variation occurring in the sensing area without any chemical modification of the surface, making it a very interesting tool in electrophysiology and biosensing applications.