Title :
Incremental learning from several different microarrays
Author :
Nikulin, Vladimir ; Rogovschi, Nicoleta ; Grozavu, Nistor
Author_Institution :
Dept. of MME, Vyatka State Univ., Kirov, Russia
Abstract :
A common phenomenon in biological experiments is that it is not possible to obtain complete measurements for all the samples. Note that some microarrays are very informative, but very expensive to have them for all the samples. However, we can use publicly available background knowledge about the potential links between the components of different microarrays (known, also, as genes). As a result, we shall translate all the selected genes in the terms of other genes. In line with the most fundamental principles of the incremental learning, those secondary genes are to be included in the regression models automatically to give the learning processes the right initial directions. The proposed method was tested online during the e-LICO data-mining Contest, where we had achieved second best score.
Keywords :
bioinformatics; data mining; genetics; learning (artificial intelligence); regression analysis; HDSS problem; Incremental Learning; bioinformatics; biological experiments; e-LICO data-mining contest; high-dimensionality-small-sample-size problem; microarrays; random permutations; regression models; relevance vector machine; secondary genes; Biological system modeling; Indexes; Kidney; Proteins; Support vector machines; Training; leave-one-out; microarray; random permutations; regression; regularization; relevance vector machine;
Conference_Titel :
Neural Networks (IJCNN), The 2013 International Joint Conference on
Conference_Location :
Dallas, TX
Print_ISBN :
978-1-4673-6128-6
DOI :
10.1109/IJCNN.2013.6706780