Fabrication and manipulation of 3D hybrid nanorobot for single cell puncture

We proposed hybrid nanorobot that can be manipulated by optical tweezers and has hybrid structure integrating functional nanomaterials. We employed femtosecond laser exposure for fabrication of the nanorobot having 3D structure with nanometric size and integrating functional nanomaterials. We succeeded in fabricating nanorobot with carbon nanotubes (CNTs) that has a high photothermal efficiency. We demonstrated single cell puncture with the nanorobot by irradiating infrared (IR) laser to CNT and generating heat on that point. The puncture shape was dependent on irradiated lase power. Furthermore, we evaluated optical manipulation characteristics of the nanorobot.