Title :
Confidence intervals for odds ratio in matching pairs under inverse sampling
Author :
ShaoPing Jiang ; Huimin Li
Author_Institution :
Sch. of Math. & Comput. Sci., Yunnan Nat. Univ., Kunming, China
Abstract :
Odds ratio is often used in matched pair design to assess the equivalence of two treatments for both prospective and retrospective clinical trials. In this context, we propose five confidence intervals estimator for the odds ratio in matching pairs under inverse sample. The performance of the proposed methods are evaluated with respect to their coverage probability and expected widths. Our empirical results show that the confidence interval based on the score statistic produce similar coverage probabilities and smaller confidence interval widths.
Keywords :
patient treatment; sampling methods; confidence interval estimator; confidence interval widths; coverage probability; inverse sampling; matched pair design; matching pairs; odds ratio; prospective clinical trials; retrospective clinical trials; score statistic; treatment equivalence; Chemotherapy; Educational institutions; Equations; Gaussian distribution; Maximum likelihood estimation; Standards; confidence interval; inverse sampling; matching pairs; odds ratio;
Conference_Titel :
Biomedical Engineering and Informatics (BMEI), 2013 6th International Conference on
Conference_Location :
Hangzhou
Print_ISBN :
978-1-4799-2760-9
DOI :
10.1109/BMEI.2013.6747010