DocumentCode :
685473
Title :
Multifractal Analysis of Disease-Related Gene Networks
Author :
Danling Wang ; Yanfei Wang
Author_Institution :
Sch. of Math. & Phys., Univ. of Sci. & Technol. Beijing, Beijing, China
Volume :
1
fYear :
2013
fDate :
28-29 Oct. 2013
Firstpage :
338
Lastpage :
341
Abstract :
In this paper, we introduce a new box-covering algorithm to compute the generalized fractal dimensions of complex networks. We apply our method on networks built on disease-related gene micro array data. For each micro array data, we compare the difference of multifractal behaviour between gene networks that reconstructed from patients and normal micorarrays. The result suggests that multifractality exists in all the gene networks we generated and the differences in the shape of the Dq curves are obvious for all micro array data sets. Thus multifractal analysis could provide a potentially useful tool for gene clustering and identification between healthy people and patients.
Keywords :
bioinformatics; complex networks; diseases; fractals; genetics; pattern clustering; Dq curves; box-covering algorithm; complex networks; disease-related gene microarray data sets; disease-related gene networks; gene clustering; generalized fractal dimensions; healthy people identification; multifractal behaviour analysis; patient identification; Bioinformatics; Cancer; Complex networks; Diabetes; Diseases; Educational institutions; Fractals; Multifractal; box-covering algrithm; complex networksg; disease-related genes;
fLanguage :
English
Publisher :
ieee
Conference_Titel :
Computational Intelligence and Design (ISCID), 2013 Sixth International Symposium on
Conference_Location :
Hangzhou
Type :
conf
DOI :
10.1109/ISCID.2013.91
Filename :
6805004
Link To Document :
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