DocumentCode
685473
Title
Multifractal Analysis of Disease-Related Gene Networks
Author
Danling Wang ; Yanfei Wang
Author_Institution
Sch. of Math. & Phys., Univ. of Sci. & Technol. Beijing, Beijing, China
Volume
1
fYear
2013
fDate
28-29 Oct. 2013
Firstpage
338
Lastpage
341
Abstract
In this paper, we introduce a new box-covering algorithm to compute the generalized fractal dimensions of complex networks. We apply our method on networks built on disease-related gene micro array data. For each micro array data, we compare the difference of multifractal behaviour between gene networks that reconstructed from patients and normal micorarrays. The result suggests that multifractality exists in all the gene networks we generated and the differences in the shape of the Dq curves are obvious for all micro array data sets. Thus multifractal analysis could provide a potentially useful tool for gene clustering and identification between healthy people and patients.
Keywords
bioinformatics; complex networks; diseases; fractals; genetics; pattern clustering; Dq curves; box-covering algorithm; complex networks; disease-related gene microarray data sets; disease-related gene networks; gene clustering; generalized fractal dimensions; healthy people identification; multifractal behaviour analysis; patient identification; Bioinformatics; Cancer; Complex networks; Diabetes; Diseases; Educational institutions; Fractals; Multifractal; box-covering algrithm; complex networksg; disease-related genes;
fLanguage
English
Publisher
ieee
Conference_Titel
Computational Intelligence and Design (ISCID), 2013 Sixth International Symposium on
Conference_Location
Hangzhou
Type
conf
DOI
10.1109/ISCID.2013.91
Filename
6805004
Link To Document