Title :
A realistic digital phantom for perfusion C-arm CT based on MRI data
Author :
Aichert, Andre ; Manhart, M.T. ; Navalpakkam, Bharath K. ; Grimm, Robert ; Hutter, Jana ; Maier, Andreas ; Hornegger, Joachim ; Doerfler, Arnd
Author_Institution :
Neuroradiologische Abt., Germany
fDate :
Oct. 27 2013-Nov. 2 2013
Abstract :
CTP is an important imaging modality for diagnosis of ischemic stroke, which is computed from of a series of consecutive CT-scans during the injection of contrast agent. Contrast flow at any point in space can be tracked as minor changes in intensity over a period of about 40 seconds to one minute, represented as a time-attenuation curve (TAC) for every voxel. This work presents an isotropic, dense, physiologically realistic and dynamic brain phantom for CT perfusion. The phantom is based on MRI scans of a volunteer and is freely available for download.
Keywords :
biomedical MRI; blood; brain; computerised tomography; haemodynamics; haemorheology; medical image processing; phantoms; MRI data; MRI scans; consecutive CT-scans; contrast agent injection; contrast flow; dense brain phantom; dynamic brain phantom; imaging modality; ischemic stroke diagnosis; isotropic brain phantom; perfusion C-arm computerised tomography; physiologically realistic brain phantom; realistic digital phantom; time-attenuation curve; Bones; Computed tomography; Magnetic resonance imaging; Noise; Phantoms; Physiology;
Conference_Titel :
Nuclear Science Symposium and Medical Imaging Conference (NSS/MIC), 2013 IEEE
Conference_Location :
Seoul
Print_ISBN :
978-1-4799-0533-1
DOI :
10.1109/NSSMIC.2013.6829168
