Title :
Combined Deadtime and Pile-up correction for the MR-compatible BrainPET Scanner
Author :
Weirich, Christoph ; Scheins, J. ; Gaens, Michaela ; Herzog, H. ; Shah, N.J.
Author_Institution :
Inst. of Neurosci. & Med. - 4, Forschungszentrum Julich, Julich, Germany
fDate :
Oct. 27 2013-Nov. 2 2013
Abstract :
Scanners in PET (Positron Emission Tomography) suffer from deadtime, i.e. the effect of sensitivity reduction with increasing count rates [1]. The reduction may be significant and its correction is a prerequisite for quantitative PET imaging. Conducting phantom studies with the Siemens 3T MR-BrainPET [2] it has been observed that deadtime is not a globally homogeneous effect but detector block dependent. Furthermore, a minor shift of crystal efficiencies on the same block due to pulse pile-up has been identified as a further component of this dynamic effect. This requires the treatment of deadtime on block and crystal level. Here, a block level deadtime correction combined with a pile-up correction is presented, implemented and assessed. The method is compared to the global deadtime correction method, as is standard in most commercial PET scanners.
Keywords :
biomedical MRI; brain; phantoms; positron emission tomography; sensitivity; Siemens 3T MR-BrainPET; combined deadtime-pile-up correction; crystal efficiencies; crystal level; detector block dependence; dynamic effect; globally homogeneous effect; level deadtime correction; magnetic resonance-compatible BrainPET scanner; phantom; positron emission tomography; pulse pile-up; quantitative PET imaging; sensitivity reduction; Computational fluid dynamics; Crystals; Detectors; Image reconstruction; Phantoms; Positron emission tomography; Sensitivity;
Conference_Titel :
Nuclear Science Symposium and Medical Imaging Conference (NSS/MIC), 2013 IEEE
Conference_Location :
Seoul
Print_ISBN :
978-1-4799-0533-1
DOI :
10.1109/NSSMIC.2013.6829401