Title :
Clinical detection of viral infection on an optofluidic chip
Author :
Measor, P. ; Zempoaltecatl, L.U. ; Parks, J.W. ; Naccache, S. ; Miller, Steven ; Chiu, C.Y. ; Hawkins, A.R. ; Schmidt, Heidemarie
Author_Institution :
Sch. of Eng., Univ. of California, Santa Cruz, Santa Cruz, CA, USA
Abstract :
We demonstrate strain-specific detection of single virus nucleic acid molecules from clinical influenza samples using an optofluidic chip. We observe a limit of detection of 104 virus copies/mL and 10 orders of magnitude dynamic range.
Keywords :
bio-optics; chemical sensors; diseases; integrated optics; lab-on-a-chip; microorganisms; molecular biophysics; optical sensors; clinical detection; clinical influenza samples; magnitude dynamic range; optofluidic chip; single virus nucleic acid molecules; strain-specific detection; viral infection; Biomedical optical imaging; Educational institutions; Influenza; Medical diagnostic imaging; Optical sensors; Optical waveguides; Probes;
Conference_Titel :
Lasers and Electro-Optics (CLEO), 2013 Conference on
Conference_Location :
San Jose, CA
