Title :
In vitro measurements of physiological glucose concentrations in biological fluids using mid-infrared spectroscopy
Author :
Liakat, Sabbir ; Bors, Kevin A. ; Tzu-Yung Huang ; Michel, Anna P. M. ; Zanghi, Eric ; Gmachl, Claire F.
Author_Institution :
Dept. of Electr. Eng., Princeton Univ., Princeton, NJ, USA
Abstract :
Predictions of glucose concentrations throughout the physiological range are obtained in vitro using partial least squares regression analysis of mid-infrared transmission spectra. Concentrations as low as 30 mg/dL are predicted to clinical accuracy.
Keywords :
infrared spectra; least mean squares methods; regression analysis; spectrochemical analysis; sugar; biological fluids; midinfrared spectroscopy; midinfrared transmission spectra; partial least squares regression analysis; physiological glucose concentration measurements; Accuracy; Calibration; In vitro; Measurement by laser beam; Physiology; Quantum cascade lasers; Sugar;
Conference_Titel :
Lasers and Electro-Optics (CLEO), 2013 Conference on
Conference_Location :
San Jose, CA
