Segmentation algorithms of chromosome images

The chromosome segmentation is the most important step in the automatic chromosome analysis system. In this paper, a few basic chromosome segmentation algorithms are investigated firstly. As a common phenomenon, the partial touching and overlapping chromosomes occur in almost every metaphase images. So, as a difficult yet vital problem, the algorithms for overlapping chromosomes are discussed in detail. The principle and the realization of these algorithms are analyzed. Results of these algorithms are compared and discussed.