Simulation of electrical field and energy deposition in tissue using gold nanoparticles

Gold nanoparticles with an optimal light absorption capacity in the near-infrared region, small size, and spherical shape are perfect to penetrate cancer cells and destroy them. Gold nanoparticles were chosen with nearly perfect spheres that ranged in size from 10 to 40 nanometers in radius. 3D simulation of gold nanoparticles was investigated through Discrete Dipole Approximation (DDA) software package DDSCAT and COMSOL Multiphysics software. The input optical pump laser was assumed to be plan wave. The distribution of the gold nanoparticles around the tumor was assumed to be uniform. The simulation shows the heat absorption peaks would be 90% at the wavelength of 8μm for gold nanoparticles with radius of 30nm and 25 nm distance from each other.