• DocumentCode
    710890
  • Title

    The role of αII-spectrin in mechanics and compressive resilience of the cell nucleus

  • Author

    Armiger, T.J. ; Dahl, K.N.

  • Author_Institution
    Carnegie Mellon Univ., Pittsburgh, PA, USA
  • fYear
    2015
  • fDate
    17-19 April 2015
  • Firstpage
    1
  • Lastpage
    2
  • Abstract
    An elastic spectrin network surrounding erythrocytes has been well characterized. Evidence suggests that a similar spectrin network may exist in the nucleus of nonerythrocytes. This work involves mechanically testing cells to determine if a spectrin network may provide elasticity to the cell nucleus.
  • Keywords
    biomechanics; biomedical measurement; blood; cellular biophysics; compressive strength; elasticity; mechanical testing; proteins; αII-spectrin; cell nucleus mechanics; compressive resilience; elastic spectrin network; elasticity; mechanical testing; nonerythrocyte nucleus; DNA; Elasticity; Fluorescence; Image coding; Particle tracking; Proteins; Resilience;
  • fLanguage
    English
  • Publisher
    ieee
  • Conference_Titel
    Biomedical Engineering Conference (NEBEC), 2015 41st Annual Northeast
  • Conference_Location
    Troy, NY
  • Print_ISBN
    978-1-4799-8358-2
  • Type

    conf

  • DOI
    10.1109/NEBEC.2015.7117147
  • Filename
    7117147