Title :
The role of αII-spectrin in mechanics and compressive resilience of the cell nucleus
Author :
Armiger, T.J. ; Dahl, K.N.
Author_Institution :
Carnegie Mellon Univ., Pittsburgh, PA, USA
Abstract :
An elastic spectrin network surrounding erythrocytes has been well characterized. Evidence suggests that a similar spectrin network may exist in the nucleus of nonerythrocytes. This work involves mechanically testing cells to determine if a spectrin network may provide elasticity to the cell nucleus.
Keywords :
biomechanics; biomedical measurement; blood; cellular biophysics; compressive strength; elasticity; mechanical testing; proteins; αII-spectrin; cell nucleus mechanics; compressive resilience; elastic spectrin network; elasticity; mechanical testing; nonerythrocyte nucleus; DNA; Elasticity; Fluorescence; Image coding; Particle tracking; Proteins; Resilience;
Conference_Titel :
Biomedical Engineering Conference (NEBEC), 2015 41st Annual Northeast
Conference_Location :
Troy, NY
Print_ISBN :
978-1-4799-8358-2
DOI :
10.1109/NEBEC.2015.7117147
