DocumentCode :
72331
Title :
Immunochromatographic Assay of Hepatitis B Surface Antigen Using Magnetic Nanoparticles as Signal Materials
Author :
Kyuha Oh ; Young Soo Choi ; Ha Young Yoon ; Nami Park ; Jooho Kim ; Young Keun Kim
Author_Institution :
R&D Center, Bio Focus Co., Ltd., Uiwang, South Korea
Volume :
50
Issue :
11
fYear :
2014
fDate :
Nov. 2014
Firstpage :
1
Lastpage :
4
Abstract :
An immunochromatographic assay for the detection of hepatitis B surface antigen (HBsAg) was developed using Fe3O4 nanoparticles as signal materials. Anti-HBsAg antibodies were labeled with carboxylated Fe3O4 particles with an average diameter of 153.6 nm, and an immunochromatography strip was constructed. The detection capability of the assay developed here is 1 ng/mL HBsAg.
Keywords :
biochemistry; biomagnetism; chemical sensors; chromatography; diseases; iron compounds; magnetic particles; molecular biophysics; nanomedicine; nanoparticles; nanosensors; proteins; Fe3O4; HBsAg; anti-HBsAg antibodies; detection capability; hepatitis B surface antigen; immunochromatographic assay; magnetic nanoparticles; signal materials; Gold; Immune system; Magnetic resonance imaging; Magnetic separation; Materials; Nanoparticles; Strips; Assay; Fe3O4 nanoparticles; hepatitis B surface antigen (HBsAg); immunochromatography; signal material;
fLanguage :
English
Journal_Title :
Magnetics, IEEE Transactions on
Publisher :
ieee
ISSN :
0018-9464
Type :
jour
DOI :
10.1109/TMAG.2014.2324613
Filename :
6971700
Link To Document :
https://search.ricest.ac.ir/dl/search/defaultta.aspx?DTC=49&DC=72331
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