• DocumentCode
    732462
  • Title

    Tether-less implantable upconverting microscale light bulbs for deep brain neural stimulation and imaging

  • Author

    Chamanzar, Maysamreza ; Garfield, David J. ; Iafrati, Jillian ; Sohal, Vikaas ; Cohen, Bruce ; Schuck, P. James ; Maharbiz, Michel M.

  • fYear
    2015
  • fDate
    10-15 May 2015
  • Firstpage
    1
  • Lastpage
    2
  • Abstract
    We demonstrate the design and fabrication of implantable micro-scale light “bulbs” comprising of parylene-encapsulated upconverting lanthanide-doped nanocrystals (absorbing near-infrared and emitting blue light) for non-invasive targeted optogenetic stimulation of local neuronal ensembles.
  • Keywords
    bioelectric potentials; biomedical optical imaging; brain; light absorption; neurophysiology; optical design techniques; optical fabrication; patient treatment; blue light emission; deep brain neural imaging; deep brain neural stimulation; implantable upconverting microscale light bulb design; implantable upconverting microscale light bulb fabrication; near-infrared light absorption; noninvasive targeted optogenetic stimulation; parylene-encapsulated upconverting lanthanide-doped nanocrystals; Absorption; Brain; Glass; Imaging; Light sources; Mice; Nanocrystals;
  • fLanguage
    English
  • Publisher
    ieee
  • Conference_Titel
    Lasers and Electro-Optics (CLEO), 2015 Conference on
  • Conference_Location
    San Jose, CA
  • Type

    conf

  • Filename
    7182893