• DocumentCode
    732468
  • Title

    Engineering the next generation of optogenetic reporters to illuminate neuronal activity

  • Author

    Campbell, Robert E.

  • Author_Institution
    Dept. of Chem., Univ. of Alberta, Edmonton, AB, Canada
  • fYear
    2015
  • fDate
    10-15 May 2015
  • Firstpage
    1
  • Lastpage
    1
  • Abstract
    The Campbell group uses protein engineering to develop fluorescent protein-based reporters for cell imaging. I will describe our most recent efforts to engineer an improved generation of reporters for calcium ion, membrane potential, and neurotransmitters.
  • Keywords
    bioelectric potentials; biomembrane transport; fluorescence; genetics; molecular biophysics; neurophysiology; proteins; Campbell group; calcium ion; cell imaging; fluorescent protein-based reporters; membrane potential; neuronal activity; neurotransmitters; optogenetic reporters; protein engineering; Biological system modeling; Fluorescence; Imaging; Neurotransmitters; Protein engineering; Proteins; Visualization;
  • fLanguage
    English
  • Publisher
    ieee
  • Conference_Titel
    Lasers and Electro-Optics (CLEO), 2015 Conference on
  • Conference_Location
    San Jose, CA
  • Type

    conf

  • Filename
    7182900