Title :
Fluorescence lifetime imaging of cellular heterogeneity in cancer drug response
Author :
Skala, Melissa C.
Author_Institution :
Dept. of Biomed. Eng. & Cancer Biol., Vanderbilt Univ., Nashville, TN, USA
Abstract :
Cancer is a heterogeneous disease, and sub-populations of cells can drive drug resistance. Fluorescence lifetime imaging of metabolic co-factors is used to monitor drug response on a cellular level, to optimize treatment strategies for patients.
Keywords :
biochemistry; biomedical optical imaging; cancer; cellular biophysics; drugs; fluorescence; patient treatment; cancer drug response; cellular heterogeneity; drug resistance; drug response; fluorescence lifetime imaging; heterogeneous disease; metabolic co-factors; treatment strategies; Biology; Biomedical engineering; Cancer; Cancer drugs; Fluorescence; Imaging;
Conference_Titel :
Lasers and Electro-Optics (CLEO), 2015 Conference on
Conference_Location :
San Jose, CA
