Title :
Optical measurement on cell membrane roughness influenced by paclitaxel and gold nanoparticles
Author :
Chau-Hwang Lee ; Lan-Lin Jang ; Huei-Jyuan Pan
Author_Institution :
Res. Center for Appl. Sci., Taipei, Taiwan
Abstract :
We measured the membrane roughness of neuroblastoma cells under the treatments of gold nanoparticles and paclitaxel. The stabilization of microtubules by paclitaxel reduced the membrane roughness. The positive charges on nanoparticles led to similar results.
Keywords :
bioMEMS; biomedical measurement; biomembranes; cellular biophysics; drugs; gold; nanomedicine; nanoparticles; surface topography measurement; Au; cell membrane roughness; gold nanoparticle treatments; microtubule stabilization; neuroblastoma cells; optical measurement; paclitaxel; positive charges; Biomembranes; Gold; Microscopy; Nanoparticles; Optical imaging; Optical microscopy; Optical variables measurement;
Conference_Titel :
Lasers and Electro-Optics (CLEO), 2015 Conference on
Conference_Location :
San Jose, CA
