Title :
Wide dynamic range specific detection of therapeutic drugs by photonic crystal microcavity arrays
Author :
Hai Yan ; Chun-Ju Yang ; Yi Zou ; Naimei Tang ; Chakravarty, Swapnajit ; Chen, Ray T.
Author_Institution :
Dept. Electr. & Comput. Eng., Univ. of Texas at Austin, Austin, TX, USA
Abstract :
Six orders of magnitude wide dynamic range (0.1ng/ml to over 100μg/ml), label-free detection of gentamicin small molecules with silicon photonic crystal microcavity biosensors multiplexed by multimode interference power splitters was experimentally demonstrated. Detection specificity was confirmed.
Keywords :
biomedical measurement; biosensors; drugs; micro-optics; microcavities; microsensors; optical beam splitters; patient treatment; photonic crystals; silicon; Si; detection specificity; gentamicin small molecules; label-free detection; multimode interference power splitters; photonic crystal microcavity arrays; silicon photonic crystal microcavity biosensors; therapeutic drugs; Drugs; Dynamic range; Microcavities; Optical sensors; Sensitivity; Sensor arrays;
Conference_Titel :
Lasers and Electro-Optics (CLEO), 2015 Conference on
Conference_Location :
San Jose, CA
