Quantifying the Multiwavelength Dispersion Effect on Dioptric Power Measurement of Intraocular Lenses

Improving technology and high demand has prompted a rapidly evolving intraocular lens (IOL) industry. To keep up with the improved designs, optical property evaluation techniques need to be adapted quickly to ensure IOL safety and efficacy. Identifying critical parameters are essential in evaluating IOL optical properties, which include temperature, medium, and test light characteristics. Here, we present a novel preclinical quantitative study of the dispersion effect that the wavelength of exposed test light has on IOL optical properties, specifically dioptric power. Dioptric power levels of IOLs were measured using a confocal laser method (CLM) when exposed to various wavelengths throughout the visible spectrum. Results showed statistically significant yet minimal focal point shift and, therefore, dioptric power changes ( $sim$0.15D) due to the effect of test light wavelength, similar to known wavelength-dependent relationships associated with changes in refractive index. Further evaluation of critical parameters can lead to an improvement of IOL product designs and overall public health.