DocumentCode :
746159
Title :
A variable range bi-phasic current stimulus driver circuitry for an implantable retinal prosthetic device
Author :
Sivaprakasam, Mohanasankar ; Liu, Wentai ; Humayun, Mark S. ; Weiland, James D.
Author_Institution :
Dept. of Electr. Eng., Univ. of California, Santa Cruz, CA, USA
Volume :
40
Issue :
3
fYear :
2005
fDate :
3/1/2005 12:00:00 AM
Firstpage :
763
Lastpage :
771
Abstract :
This paper reports a driver circuitry to generate bi-phasic (anodic and cathodic) current pulses for stimulating the retinal layer through electrodes which is part of a retinal prosthetic device for implants in blind patients affected by retinitis pigmentosa (RP) and age-related macular degeneration (AMD). Dual voltage architecture is used to halve the number of interface leads from the chip to the stimulation sites compared to a single voltage supply. The driver circuitry is designed to deliver currents with six bit resolution for a wide range of full scale currents up to 600 μA. To cater to the varying stimulus requirements among patients and different regions of the retina, variable gain architecture is used to achieve fine resolution even for a narrow range of stimulus. 1:8 demultiplexing feature is embedded within the output stage thus allowing one DAC for eight outputs. A novel charge cancellation circuitry with current limiting capability is implemented to discharge the electrodes for medical safety. Measurement results of a prototype chip fabricated in 1.5-μm CMOS technology are presented.
Keywords :
CMOS integrated circuits; biomedical electrodes; digital-analogue conversion; driver circuits; eye; prosthetic power supplies; 1.5 micron; 600 muA; CMOS technology; DAC; age-related macular degeneration; bi-phasic driver circuitry; biomedical circuits; blind patients; charge cancellation circuitry; current limiting capability; current pulses; current stimulus driver circuitry; dual voltage architecture; fine resolution; functional electrical stimulation; implantable devices; implantable retinal prosthetic device; medical safety; retinal layer; retinitis pigmentosa; stimulation sites; variable gain architecture; variable range driver circuitry; CMOS technology; Driver circuits; Electrodes; Implants; Pigmentation; Prosthetics; Pulse circuits; Pulse generation; Retina; Voltage; Biomedical; functional electrical stimulation (FES); implantable devices; microstimulator; retinal prosthesis;
fLanguage :
English
Journal_Title :
Solid-State Circuits, IEEE Journal of
Publisher :
ieee
ISSN :
0018-9200
Type :
jour
DOI :
10.1109/JSSC.2005.843630
Filename :
1408097
Link To Document :
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