• DocumentCode
    746714
  • Title

    Digital Image Elasto-Tomography: Combinatorial and Hybrid Optimization Algorithms for Shape-Based Elastic Property Reconstruction

  • Author

    Peters, Ashton ; Chase, J. Geoffrey ; Van Houten, Elijah E W

  • Author_Institution
    Boundary Lifesciences, Inc., Christchurch
  • Volume
    55
  • Issue
    11
  • fYear
    2008
  • Firstpage
    2575
  • Lastpage
    2583
  • Abstract
    Results from the application of three nonlinear stiffness reconstruction algorithms to two simple cylindrical geometries are presented in this paper. Finite-element simulated harmonic motion data with added noise were initially used to represent a measured surface displacement dataset for each geometry. This motion was used as input to gradient-descent, combinatorial optimization, and hybrid reconstruction algorithms that aimed to reconstruct two shape-based parameters describing the internal stiffness of the geometry. Both the combinatorial optimization and hybrid algorithms showed significant advantages in reconstructed parameter accuracy when compared with the traditional gradient-descent approach, with success metrics improving by 13-28%. Results from the hybrid algorithm applied to silicone phantom displacements demonstrated for the first time the ability of this type of algorithm to reconstruct internal stiffness using only experimentally measured surface motion data. Improvements in the sophistication of the hybrid approach should lead to improved accuracy in reconstructed solutions, as well as enabling reconstructions where the geometry is less straightforward.
  • Keywords
    biological tissues; biomechanics; cancer; combinatorial mathematics; finite element analysis; image reconstruction; medical image processing; optical tomography; optimisation; cancerous breast tissue; combinatorial optimization algorithms; digital image elasto-tomography; elastic properties; finite-element simulated harmonic motion; human tissue; hybrid optimization algorithms; nonlinear stiffness reconstruction algorithms; shape-based elastic property reconstruction; silicone phantom displacements; surface displacement dataset; Digital images; Displacement measurement; Finite element methods; Geometry; Image reconstruction; Motion measurement; Noise shaping; Reconstruction algorithms; Solid modeling; Surface reconstruction; Biomedical imaging; combinatorial mathematics; finite-element methods; inverse problems; Algorithms; Elasticity; Elasticity Imaging Techniques; Finite Element Analysis; Humans; Image Enhancement; Image Processing, Computer-Assisted; Phantoms, Imaging; Silicones; Tomography;
  • fLanguage
    English
  • Journal_Title
    Biomedical Engineering, IEEE Transactions on
  • Publisher
    ieee
  • ISSN
    0018-9294
  • Type

    jour

  • DOI
    10.1109/TBME.2008.2001132
  • Filename
    4539792