Title :
A Bayesian Bounded Asymmetric Mixture Model With Segmentation Application
Author :
Thanh Minh Nguyen ; Wu, Q. M. Jonathan ; Mukherjee, Dipankar ; Hui Zhang
Author_Institution :
Dept. of Electr. & Comput. Eng., Univ. of Windsor, Windsor, ON, Canada
Abstract :
Segmentation of a medical image based on the modeling and estimation of the tissue intensity probability density functions via a Gaussian mixture model has recently received great attention. However, the Gaussian distribution is unbounded and symmetrical around its mean. This study presents a new bounded asymmetric mixture model for analyzing both univariate and multivariate data. The advantage of the proposed model is that it has the flexibility to fit different shapes of observed data such as non-Gaussian, nonsymmetric, and bounded support data. Another advantage is that each component of the proposed model has the ability to model the observed data with different bounded support regions, which is suitable for application on image segmentation. Our method is intuitively appealing, simple, and easy to implement. We also propose a new method to estimate the model parameters in order to minimize the higher bound on the data negative log-likelihood function. Numerical experiments are presented where the proposed model is tested in various images from simulated to real 3- D medical ones.
Keywords :
Bayes methods; Gaussian distribution; biological tissues; image segmentation; medical image processing; parameter estimation; Bayesian bounded asymmetric mixture model; Gaussian distribution; Gaussian mixture model; bounded support data; bounded support regions; data negative log-likelihood function; medical image segmentation; model parameter estimation; multivariate data; nonGaussian data; nonsymmetric data; real 3- D medical image; segmentation application; tissue intensity probability density function estimation; tissue intensity probability density function modeling; univariate data; Bayesian estimation; bounded support regions; medical image segmentation; negative log-likelihood function; non-Gaussian; nonsymmetric;
Journal_Title :
Biomedical and Health Informatics, IEEE Journal of
DOI :
10.1109/JBHI.2013.2264749