Title :
Computation of the potential distribution in a four-layer anisotropic concentric spherical volume conductor
Author :
Zhou, Hong ; Van Oosterom, Adriaan
Author_Institution :
Lab. of Med. Phys. & Biophys.,Nijmegen Univ., Netherlands
Abstract :
A method for solving the potential distribution in a multilayer anisotropic concentric spherical volume conductor has been tested and found to be numerically unstable. It is demonstrated how these numerical difficulties can be avoided. The method is extended by lifting the previously imposed restriction on the innermost region to be isotropic. A convergence criterion for determining the required number of terms in the final series expansion is proposed. The influences of radial and tangential conductivity values of the skull and brain tissue on the dipole-induced potential are investigated.
Keywords :
bioelectric potentials; physiological models; 4-layer anisotropic concentric spherical volume conductor; brain tissue; convergence criterion; dipole-induced potential; numerical difficulties; numerical instability; potential distribution computation; radial conductivity; series expansion; skull; tangential conductivity; Anisotropic magnetoresistance; Biomedical computing; Biomedical engineering; Brain modeling; Conductivity; Conductors; Distributed computing; Electroencephalography; Head; Skull; Algorithms; Brain; Cerebrospinal Fluid; Electric Conductivity; Electroencephalography; Electromagnetics; Electrophysiology; Evoked Potentials; Humans; Models, Biological; Scalp; Skull;
Journal_Title :
Biomedical Engineering, IEEE Transactions on