Title :
Focusing fluids and light
Author :
Mao, Xiaole ; Huang, Tony Jun
Author_Institution :
Dept. of Bioeng., Penn State Univ., University Park, PA
fDate :
3/1/2008 12:00:00 AM
Abstract :
There exist two major technical challenges when developing on-chip single- particle detection systems: focusing the particles and focusing the light. Flow cytometry is used to measure the optical and fluorescence characteristics of single cells while cells pass through an optical interrogation area (with dimensions on the order of several micrometers to tens of micrometers) that is defined by a focused laser beam.
Keywords :
bioMEMS; cellular biophysics; laser applications in medicine; flow cytometry; focused laser beam; light focusing; on-chip single-particle detection systems; optical interrogation; particles focusing; single cells; Biomedical optical imaging; Coaxial components; Fluorescence; Hydrodynamics; Laser excitation; Microfluidics; Optical devices; Optical sensors; Optical waveguides; System-on-a-chip;
Journal_Title :
Nanotechnology Magazine, IEEE
DOI :
10.1109/MNANO.2008.920048
