• DocumentCode
    773356
  • Title

    Building three-dimensional ribonucleic acid structures

  • Author

    Major, François

  • Author_Institution
    Dept. d´´Inf. et de Recherche Oper., Montreal Univ., Que., Canada
  • Volume
    5
  • Issue
    5
  • fYear
    2003
  • Firstpage
    44
  • Lastpage
    53
  • Abstract
    MC-Sym is an intelligent computer system that builds 3D ribonucleic acid structures from low-resolution data by combining symbolic and numerical computations. Specifically, the symbolic step generates all-atom sketches of 3D structures that nonlinear optimization methods can refine in a second step.
  • Keywords
    biology computing; expert systems; macromolecules; nonlinear programming; symbol manipulation; 3D ribonucleic acid structures; MC-Sym; all-atom sketches; intelligent computer system; low-resolution data; nonlinear optimization methods; numerical computations; symbolic computations; three-dimensional ribonucleic acid structures; Biochemistry; Biology computing; Buildings; Intelligent structures; Intelligent systems; Laboratories; Nuclear magnetic resonance; Optimization methods; Proteins; RNA;
  • fLanguage
    English
  • Journal_Title
    Computing in Science & Engineering
  • Publisher
    ieee
  • ISSN
    1521-9615
  • Type

    jour

  • DOI
    10.1109/MCISE.2003.1225860
  • Filename
    1225860
    • Link To Document
    https://search.isc.ac/dl/search/defaultta.aspx?DTC=49&DC=773356