The Design and Manufacture of an Annular Variable-Focusing Collimator for Highsensitivity Brain SPECT

Author

Ouyang, Jinsong ; Fakhri, G.E. ; Xia, Weishi ; Kijewski, Marie Foley ; Genna, Sebastian

Author_Institution

Dept. of Radiol., Harvard Med. Sch., Boston, MA

Volume

53

Issue

5

fYear

2006

Firstpage

2613

Lastpage

2618

Abstract

Sensitivity near the center of the brain is critical for some clinical applications of brain SPECT, especially for those applications which require dynamic imaging. We have designed and built a novel collimator for the CeraSPECT dedicated brain SPECT system which uses variable focusing to increase the sensitivity for central regions of its field of view. The sensitivity at the center of the field of view is increased by a factor of two compared to the standard three-segment parallel-hole collimator; this sensitivity gain is achieved without compromising spatial resolution

Keywords

brain; collimators; neurophysiology; single photon emission computed tomography; CeraSPECT; annular variable-focusing collimator; high-sensitivity brain SPECT; sensograde collimator; spatial resolution; Alzheimer´s disease; Brain; Cameras; Focusing; Manufacturing; Optical collimators; Parameter estimation; Parkinson´s disease; Single photon emission computed tomography; Spatial resolution; Annular brain SPECT; CeraSPECT; SensOgrade collimator; variable-focusing collimator;

fLanguage

English

Journal_Title

Nuclear Science, IEEE Transactions on

Publisher

ieee

ISSN

0018-9499

Type

jour

DOI

10.1109/TNS.2006.877151

Filename

1710246