Visualization of calcium activity in nerve cells

Author

Sobierajski, Lisa M. ; Avila, Ricardo S. ; O´Malley, Donald M. ; Wang, Sidney ; Kaufman, Arie E.

Author_Institution

Gen. Electr. Corp. Res. & Dev. Center, Schenectady, NY, USA

Volume

15

Issue

4

fYear

1995

fDate

7/1/1995 12:00:00 AM

Firstpage

55

Lastpage

61

Abstract

Calcium plays an important role in many cellular functions. This investigation of its role in nervous system behavior uses imaging techniques, confocal microscopy, and the VolVis volume visualization system. The use of VolVis provided substantial assistance in the study of cellular calcium dynamics and in monitoring neural network activity. It yielded geometric details that facilitated our understanding of the behavior of calcium indicators inside nerve cells and led to a new view of the calcium permeability of the nuclear envelope. It has also produced anatomical details that significantly facilitated the development of a technique to directly visualize the activity of neuron populations while simultaneously observing vertebrate behavior

Keywords

biology computing; calcium; data visualisation; neural nets; neurophysiology; zoology; Ca; VolVis volume visualization system; anatomical details; cellular Ca dynamics; confocal microscopy; geometric details; imaging techniques; nerve cell Ca activity visualization; nervous system behavior; neural network activity monitoring; neuron populations; nuclear envelope permeability; vertebrate behavior; Biological neural networks; Calcium; Cellular networks; Cellular neural networks; Microscopy; Monitoring; Nervous system; Neural networks; Permeability; Visualization;

fLanguage

English

Journal_Title

Computer Graphics and Applications, IEEE

Publisher

ieee

ISSN

0272-1716

Type

jour

DOI

10.1109/38.391491

Filename

391491