An intelligent system for vertebrate promoter recognition

Author

Bajic, Vladimir B. ; Chong, Allen ; Seah, Seng Hong ; Brusic, Vladimir

Volume

17

Issue

4

fYear

2002

Firstpage

64

Lastpage

70

Abstract

A promoter, the DNA region encompassing a gene´s transcription start site, largely controls the biological activation of a gene. Dragon Promoter Finder, an advanced system for promoter recognition in vertebrates, uses a collection of models based on multi-sensor integration, signal processing and artificial neural networks. The system minimizes the number of false-positive predictions for various pre-specified sensitivity levels and exhibits several times higher accuracy than other compared systems.

Keywords

DNA; artificial intelligence; biology computing; genetics; neural nets; pattern recognition; sensitivity; sensor fusion; signal processing; zoology; DNA region; Dragon Promoter Finder; accuracy; artificial neural networks; biological gene activation; false-positive prediction minimization; gene transcription start site; intelligent system; multi-sensor integration; sensitivity levels; signal processing; vertebrate promoter recognition; Artificial neural networks; Bioinformatics; Character recognition; DNA; Face recognition; Intelligent systems; Laboratories; Search methods; Sequences; Signal analysis;

fLanguage

English

Journal_Title

Intelligent Systems, IEEE

Publisher

ieee

ISSN

1541-1672

Type

jour

DOI

10.1109/MIS.2002.1024754

Filename

1024754