Title :
Experimental verification of theoretical in vivo ultrasound heating using cobalt detected magnetic resonance
Author :
Smith, N.B. ; Webb, A.G. ; Ellis, D.S. ; O´Brien, William
Author_Institution :
Dept. of Electr. & Comput. Eng., Illinois Univ., Urbana, IL, USA
fDate :
7/1/1995 12:00:00 AM
Abstract :
Conventional methods of measuring heating in vivo are invasive and therefore interfere with heat propagation. For the first time, ultrasound-induced temperature increases in living specimens have been estimated theoretically and measured experimentally using a noninvasive technique. In vivo ultrasound-induced temperature increases in the livers of rats show consistent results between: (1) a theoretical ultrasound point-source solution for a measured ultrasound source power of 4.3 W (2/spl deg/C) and (2) a sensitive noninvasive magnetic resonance method with the cobalt (III) nucleus as a probe (2.0/spl plusmn/1.2/spl deg/C).<>
Keywords :
biological NMR; biological effects of acoustic radiation; biomedical NMR; biomedical ultrasonics; biothermics; liver; 2 C; 4.3 W; Co; cobalt (III) nucleus; heat propagation; in vivo ultrasound heating; livers; living specimens; magnetic resonance; noninvasive technique; point-source; rats; Estimation theory; Heating; In vivo; Liver; Noninvasive treatment; Rats; Temperature sensors; Time measurement; Ultrasonic imaging; Ultrasonic variables measurement;
Journal_Title :
Ultrasonics, Ferroelectrics, and Frequency Control, IEEE Transactions on
