• DocumentCode
    810473
  • Title

    Stokes shift emission spectroscopy of human tissue and key biomolecules

  • Author

    Alfano, R.R. ; Yang, Yuanlong

  • Author_Institution
    Phys. Dept., City Univ. of New York, NY, USA
  • Volume
    9
  • Issue
    2
  • fYear
    2003
  • Firstpage
    148
  • Lastpage
    153
  • Abstract
    The Stokes-shifted emission spectra were measured for various photoactive biomolecules in aqueous solution and tissue such as tryptophan, collagen, nicotinamide adenine dinucleotide, and flavin. Information is obtained on the molecular activity in the tissue. This new approach allows for the extraction of some new information not obtained from excitation and/or fluorescence spectroscopy for a single spectral scan.
  • Keywords
    biological techniques; biological tissues; cancer; diseases; fluorescence spectroscopy; molecular biophysics; proteins; spectral line shift; Stokes shift emission spectroscopy; absorption; aqueous solution; atherosclerosis; cancer; collagen; disease state; flavin; fluorescence; human tissue; key biomolecules; molecular activity; nicotinamide adenine dinucleotide; photoactive biomolecules; precancer; single spectral scan; tryptophan; Absorption; Amino acids; Biomedical optical imaging; Fluorescence; Humans; Molecular biophysics; Physics; Proteins; Spectroscopy; Stimulated emission;
  • fLanguage
    English
  • Journal_Title
    Selected Topics in Quantum Electronics, IEEE Journal of
  • Publisher
    ieee
  • ISSN
    1077-260X
  • Type

    jour

  • DOI
    10.1109/JSTQE.2003.811285
  • Filename
    1238963