Robust closed-loop control of isometric muscle force using pulsewidth modulation

The design of feedback controllers to accurately and robustly regulate the properties of electrically stimulated muscle is considered. Reliable, precise control is necessary for the development of neuroprosthetic devices to improve gradation and repeatability of force. A digital closed-loop controller has been developed which regulates muscle force by modulating the pulsewidth of a constant-amplitude electrical simulation pulse train. This controller has been evaluated in slow- and fast-twitch muscles (cat soleus and plantaris) in acute experiments. In isometric tests, it was found to regulate muscle force with low sensitivity to modeling errors and disturbances while satisfying stability, repeatability, linearity, and step/ramp response criteria over a wide range of commands.