Spectral Peak-Shift Estimation With Wavelength Dependent Sources and Detectors

Author

Hastings, J.T.

Author_Institution

Dept. of Electr. & Comput. Eng., Univ. of Kentucky, Lexington, KY

Volume

56

Issue

10

fYear

2008

Firstpage

5269

Lastpage

5272

Abstract

This correspondence extends Karl and Pien´s [ldquoHigh-Resolution Biosensor Spectral Peak Shift Estimation,rdquo IEEE Transactions on Signal Processing, vol 53, no. 12, pp. 4631-4639, December 2005] approach to spectral-shift estimation for optical sensors to account for wavelength dependent illumination sources and detectors. Relaxing the assumption of spectrally uniform source power and detector efficiency alters the previously derived Cramer-Rao bound and maximum-likelihood estimator. The new estimator offers significantly reduced error compared to the wavelength invariant estimator and common ad hoc estimators.

Keywords

biosensors; maximum likelihood estimation; optical sensors; spectral line shift; Cramer-Rao bound; high-resolution biosensor; maximum-likelihood estimator; optical sensors; spectral peak-shift estimation; spectral-shift estimation; wavelength dependent detectors; wavelength dependent illumination sources; wavelength dependent sources; CramÉr–Rao lower bound; Cramer-Rao lower bound; optical sensors; spectral peak-shift estimation;

fLanguage

English

Journal_Title

Signal Processing, IEEE Transactions on

Publisher

ieee

ISSN

1053-587X

Type

jour

DOI

10.1109/TSP.2008.928954

Filename

4579690