Image Intensification of X-Ray Diffraction Patterns from Biological Structures

An image intensifier has been used to record two dimensional X-ray diffraction patterns. The details and characteristics of the system in current use are described. This system provides for the conversion of X-rays to visible light, intensification of this light for integration on a TV vidicon target, on-line computer controlled scan and readout to disk, and subsequent computer analysis of the data. The system is particularly useful for the study of weakly diffracting specimens, samples where radiation damage dictates minimal exposure, and structures where dynamic processes are involved. Results obtained to date are discussed. Comparisons are made of this system with alternate recording systems, including film and electronic devices. The potential usefulness of this system for studies utilizing high intensity synchrotron radiation is discussed.