Quantitative analysis of reconstructed 3-D coronary arterial tree and intracoronary devices

Traditional quantitative coronary angiography is performed on two-dimensional (2-D) projection views. These views are chosen by the angiographer to minimize vessel overlap and foreshortening. With 2-D projection views that are acquired in this nonstandardized fashion, however, there is no way to know or estimate how much error occurs in the QCA process. Furthermore, coronary arteries possess a curvilinear shape and undergo a cyclical deformation due to their attachment to the myocardium. Therefore, it is necessary to obtain three-dimensional (3-D) information to best describe and quantify the dynamic curvilinear nature of the human coronary artery. Using a patient-specific 3-D coronary reconstruction algorithm and routine angiographic images, a new technique is proposed to describe: (1) the curvilinear nature of 3-D coronary arteries and intracoronary devices; (2) the magnitude of the arterial deformation caused by intracoronary devices and due to heart motion; and (3) optimal view(s) with respect to the desired "pathway" for delivering intracoronary devices.