Title :
Hybridization in Nonbinary Trees
Author :
Linz, Simone ; Semple, Charles
Author_Institution :
Dept. of Bioinf., Heinrich-Heine Univ., Dusseldorf
Abstract :
Reticulate evolution - the umbrella term for processes like hybridization, horizontal gene transfer, and recombination - plays an important role in the history of life of many species. Although the occurrence of such events is widely accepted, approaches to calculate the extent to which reticulation has influenced evolution are relatively rare. In this paper, we show that the NP-hard problem of calculating the minimum number of reticulation events for two (arbitrary) rooted phylogenetic trees parameterized by this minimum number is fixed-parameter tractable.
Keywords :
evolution (biological); genetics; molecular biophysics; trees (mathematics); NP-hard problem; horizontal gene transfer; nonbinary tree hybridization; phylogenetic trees; recombination; reticulate evolution; reticulation events; Combinatorial algorithms; Network problems; Algorithms; Computational Biology; Evolution, Molecular; Hybridization, Genetic; Models, Genetic; Phylogeny;
Journal_Title :
Computational Biology and Bioinformatics, IEEE/ACM Transactions on
DOI :
10.1109/TCBB.2008.86