• DocumentCode
    84308
  • Title

    The Body Printed: How 3-D Printing Could Change the Face of Modern Medicine?And Why That Future Is Still So Far Away

  • Author

    Fischer, Shannon

  • Volume
    4
  • Issue
    6
  • fYear
    2013
  • fDate
    Nov. 2013
  • Firstpage
    27
  • Lastpage
    31
  • Abstract
    It takes only a few minutes for the NovoGen MMX to print out a chunk of human liver cells. It´s a small chunk, only 4-mm wide and 20 cell layers thick, which wouldn´t do much good in a human patient. But at a cellular level, this tiny swatch of machine-made flesh has all the essential ingredients of an original organ: tight hexagons of hepatocytes and fatty stellate cells and endothelial cells gathered into nascent capillaries. It produces cholesterol, albumin, and detoxifying P450 enzymes. After it is printed, the ensemble can survive for almost an entire week-nearly triple the endurance of classic two-dimensional (2-D) liver cultures.
  • Keywords
    cellular biophysics; enzymes; liver; molecular biophysics; albumin; cholesterol; detoxifying P450 enzymes; endothelial cells; fatty stellate cells; hepatocytes; human liver cells; human patient; machine-made flesh; nascent capillaries; two-dimensional liver cultures; Biomedical imaging; Printing; Three dimensional displays; Animals; Bioprinting; Biotechnology; Humans; Mice; Tissue Engineering;
  • fLanguage
    English
  • Journal_Title
    Pulse, IEEE
  • Publisher
    ieee
  • ISSN
    2154-2287
  • Type

    jour

  • DOI
    10.1109/MPUL.2013.2279618
  • Filename
    6656993