Title :
An extracellular matrix extract for tissue-engineered cartilage
Author :
Lum, Leon Y. ; Cher, Nicholas L C ; Williams, Christopher G. ; Elisseeff, Jennifer H.
Author_Institution :
Dept. of Biomed. Eng., Johns Hopkins Univ., Baltimore, MD, USA
Abstract :
Cartrigel modulates the chondrogenic effect of TGF-β3 on mesenchymal stem cells in photopolymerizing hydrogels. Tissue engineering of cartilage in photopolymerizing PEG-based scaffolds may benefit from the incorporation of ECM extracts for greater control of cell behavior.
Keywords :
biological tissues; cellular biophysics; molecular biophysics; patient treatment; proteins; tissue engineering; cartilage; cell behavior; photopolymerizing PEG-based scaffolds; tissue engineering; Analysis of variance; Chemicals; DNA; Extracellular; Immune system; Polymers; Proteins; RNA; Sequences; Stem cells;
Journal_Title :
Engineering in Medicine and Biology Magazine, IEEE
DOI :
10.1109/MEMB.2003.1256275
