Size Dependent In-Vitro Heating With Polyethylene Glycol Coated Magnetic Nanoparticles

Author

Bonder, M.J. ; Gallo, D. ; Srinivasan, B. ; Hadjipanayis, G.C.

Author_Institution

Dept. of Phys. & Astron., Delaware Univ., Newark, DE

Volume

43

Issue

6

fYear

2007

fDate

6/1/2007 12:00:00 AM

Firstpage

2457

Lastpage

2458

Abstract

Magnetic nanoparticles represent a nanotechnology for the treatment of cancer as a result of the localized thermal gradients produced in response to an oscillating magnetic field. Using a sodium borohydride reduction of ferrous chloride in the presence of carboxyl terminated polyethylene glycol this study looks at the contribution of particle size to the achievable temperature using a 500 kHz excitation field. By magnetically separating the as-synthesized sample it was found that the smaller particles within the sample are more effective heating elements.

Keywords

biomagnetism; cancer; heat treatment; hyperthermia; magnetic particles; magnetic separation; nanobiotechnology; nanoparticles; particle size; polymer films; 500 kHz; cancer treatment; magnetic nanoparticles; magnetical separation; nanotechnology; oscillating magnetic field; particle size; polyethylene glycol coating; size dependent in-vitro heating; Cancer; Conducting materials; Frequency; Heating; In vitro; Magnetic confinement; Magnetic materials; Magnetic separation; Nanoparticles; Polyethylene; Chemical synthesis; hyperthermia; magnetic nanoparticles;

fLanguage

English

Journal_Title

Magnetics, IEEE Transactions on

Publisher

ieee

ISSN

0018-9464

Type

jour

DOI

10.1109/TMAG.2007.894125

Filename

4202659