Title :
The Determination of Platinum in Human Tissues with PIXE
Author :
Dikhoff, T.G.M.H. ; van der Heide, J.A. ; Prins, M. ; Vie, J. G Mc
Author_Institution :
Eindhoven University of Technology, 5612 AZ Eindhoven, The Netherlands
fDate :
4/1/1983 12:00:00 AM
Abstract :
Platinum levels as well as trace element concentrations in samples from cis-platin treated patients have been measured using the PIXE technique. The results were verified by neutron activation analysis for some elements. Spectral interferences of the platinum Lß peak and selenium K¿ have been solved by introducing a germanium layer as a selective absorber. The experiments are done in the frame work of a project on the assesment of the toxicity of cytostatic platinum compounds. Preliminary results for liver, kidney and heart tissues are shown.
Keywords :
Activation analysis; Heart; Humans; Liver; Medical treatment; Neutrons; Plasma measurements; Platinum; X-ray detection; Yttrium;
Journal_Title :
Nuclear Science, IEEE Transactions on
DOI :
10.1109/TNS.1983.4332523
