• DocumentCode
    865618
  • Title

    The Determination of Platinum in Human Tissues with PIXE

  • Author

    Dikhoff, T.G.M.H. ; van der Heide, J.A. ; Prins, M. ; Vie, J. G Mc

  • Author_Institution
    Eindhoven University of Technology, 5612 AZ Eindhoven, The Netherlands
  • Volume
    30
  • Issue
    2
  • fYear
    1983
  • fDate
    4/1/1983 12:00:00 AM
  • Firstpage
    1329
  • Lastpage
    1331
  • Abstract
    Platinum levels as well as trace element concentrations in samples from cis-platin treated patients have been measured using the PIXE technique. The results were verified by neutron activation analysis for some elements. Spectral interferences of the platinum Lß peak and selenium K¿ have been solved by introducing a germanium layer as a selective absorber. The experiments are done in the frame work of a project on the assesment of the toxicity of cytostatic platinum compounds. Preliminary results for liver, kidney and heart tissues are shown.
  • Keywords
    Activation analysis; Heart; Humans; Liver; Medical treatment; Neutrons; Plasma measurements; Platinum; X-ray detection; Yttrium;
  • fLanguage
    English
  • Journal_Title
    Nuclear Science, IEEE Transactions on
  • Publisher
    ieee
  • ISSN
    0018-9499
  • Type

    jour

  • DOI
    10.1109/TNS.1983.4332523
  • Filename
    4332523
    • Link To Document
    https://search.isc.ac/dl/search/defaultta.aspx?DTC=49&DC=865618